Endocrine Abstracts

Background: Heat shock protein 60 (HSP60), a potentially homeostatic antigen, has been shown to be involved in physiological and non-physiological conditions. Experimental data is supporting the role of HSP60 in placental and mitochondrial steroidogenesis. Under stress conditions, HSP60 are translocated into the endothelial-cell plasma membrane and the extracellular space, promoting the atherosclerotic process. Aim: We decided to investigate the associat...